The CAC 40 fell 2.2% to close at 8,253 on Wednesday as investors grappled with mounting political uncertainty in France and renewed tensions in the Middle East. Le Pen confirmed her intention to mount a fourth presidential campaign despite legal challenges stemming from her conviction for the misuse of public funds. Recent polls show her party leading. Meanwhile, US President Trump said the memorandum of understanding with Iran to end the conflict was "over," reviving concerns over potential disruptions to global energy supplies. Higher oil prices renewed fears of energy-driven inflation and higher interest rates. Luxury stocks declined as risk aversion rose, with LVMH losing 2.4%, L'Oreal down 2.3%, Hermes losing 4.5%, and Kering shedding 5.2%. Industrials traded lower, with Airbus down 3.1% and Safran falling 4.5%. Financials lost as bond yields moved higher, with BNP Paribas down 3.9% and Societe Generale losing 5.7%. In contrast, TotalEnergies gained 2.1% on higher oil prices.